4A0P

Crystal structure of LRP6P3E3P4E4

4A0P の概要

• エントリーDOI: 10.2210/pdb4a0p/pdb
• 分子名称: LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: signaling, lrp6, wnt signalling, wnt3a, dkk1, mesd
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 72812.04

構造登録者

Chen, S.,Malinauskas, T.,Aricescu, A.R.,Siebold, C.,Jones, E.Y. (登録日: 2011-09-11, 公開日: 2011-10-26, 最終更新日: 2023-12-20)

• 主引用文献: Chen, S.,Bubeck, D.,Macdonald, B.T.,Liang, W.X.,Mao, J.H.,Malinauskas, T.,Llorca, O.,Aricescu, A.R.,Siebold, C.,He, X.,Jones, E.Y.; Structural and Functional Studies of Lrp6 Ectodomain Reveal a Platform for Wnt Signaling.; Dev.Cell, 21:848-, 2011; PubMed: 22000855; DOI: 10.1016/J.DEVCEL.2011.09.007

実験手法

X-RAY DIFFRACTION (1.9 Å)