4ZFX

Siderocalin-mediated recognition and cellular uptake of actinides

Summary for 4ZFX

Entry DOI	10.2210/pdb4zfx/pdb
Descriptor	Neutrophil gelatinase-associated lipocalin, THORIUM ION, N,N',N''-[(3S,7S,11S)-2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl]tris(2,3-dihydroxybenzamide), ... (5 entities in total)
Functional Keywords	metal binding protein-inhibitor complex, metal binding protein/inhibitor
Biological source	Homo sapiens (Human)
Cellular location	Secreted : P80188
Total number of polymer chains	3
Total formula weight	64232.96
Authors	Allred, B.E.,Rupert, P.B.,Gauny, S.S.,An, D.D.,Ralston, C.Y.,Sturzbecher-Hoehne, M.,Strong, R.K.,Abergel, R.J. (deposition date: 2015-04-22, release date: 2015-08-05, Last modification date: 2023-09-27)
Primary citation	Allred, B.E.,Rupert, P.B.,Gauny, S.S.,An, D.D.,Ralston, C.Y.,Sturzbecher-Hoehne, M.,Strong, R.K.,Abergel, R.J. Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides. Proc.Natl.Acad.Sci.USA, 112:10342-10347, 2015 Cited by PubMed: 26240330 DOI: 10.1073/pnas.1508902112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation