4YVF
Structure of S-adenosyl-L-homocysteine hydrolase
Summary for 4YVF
Entry DOI | 10.2210/pdb4yvf/pdb |
Descriptor | Adenosylhomocysteinase, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-{[5-chloro-2-(4-chlorophenoxy)phenyl](2-{[2-(methylamino)ethyl]amino}-2-oxoethyl)amino}-N-(1,3-dihydro-2H-isoindol-2-yl)-N-methylacetamide, ... (4 entities in total) |
Functional Keywords | sahh, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 97989.76 |
Authors | Akiko, K. (deposition date: 2015-03-20, release date: 2015-11-25, Last modification date: 2024-03-20) |
Primary citation | Nakao, A.,Suzuki, H.,Ueno, H.,Iwasaki, H.,Setsuta, T.,Kashima, A.,Sunada, S. Discovery and structural analyses of S-adenosyl-L-homocysteine hydrolase inhibitors based on non-adenosine analogs. Bioorg.Med.Chem., 23:4952-4969, 2015 Cited by PubMed: 26037610DOI: 10.1016/j.bmc.2015.05.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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