4YM0

Crystal structure of the human galectin-4 C-terminal carbohydrate recognition domain in complex with lacto-N-tetraose (LNT)

Summary for 4YM0

Entry DOI	10.2210/pdb4ym0/pdb
Related	4YLZ 4YM1 4YM2 4YM3
Related PRD ID	PRD_900004
Descriptor	Galectin-4, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	galectin, lectin, carbohydrate binding protein, lacto-n-tetraose, carbohydrate recognition, beta sandwich, sugar binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	70082.16
Authors	Bum-Erdene, K.,Blanchard, H. (deposition date: 2015-03-06, release date: 2015-07-01, Last modification date: 2024-02-28)
Primary citation	Bum-Erdene, K.,Leffler, H.,Nilsson, U.J.,Blanchard, H. Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens. Febs J., 282:3348-3367, 2015 Cited by PubMed: 26077389 DOI: 10.1111/febs.13348 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation