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4Y4K

Crystal structure of the mCD1d/EF77/iNKTCR ternary complex

Summary for 4Y4K
Entry DOI10.2210/pdb4y4k/pdb
Related4Y16 4Y2D 4Y4F 4Y4H
DescriptorAntigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, chimeric TCR Valpha14Jalpha18 chain (mouse variable, human constant domain), ... (7 entities in total)
Functional Keywordsmhc-fold, ig-fold, glycolipid antigen presentation, t cell receptor, immune system
Biological sourceMus musculus (Mouse)
More
Total number of polymer chains4
Total formula weight96186.78
Authors
Zajonc, D.M.,Birkholz, A.M. (deposition date: 2015-02-10, release date: 2015-05-27, Last modification date: 2023-09-27)
Primary citationBirkholz, A.,Nemcovic, M.,Yu, E.D.,Girardi, E.,Wang, J.,Khurana, A.,Pauwels, N.,Franck, R.W.,Tsuji, M.,Howell, A.,Calenbergh, S.,Kronenberg, M.,Zajonc, D.M.
Structural modifications of alphaGalCer in both lipid and carbohydrate moiety influence activation of murine and human iNKT cells
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

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