4XRO
Disulfide stabilized HIV-1 CA hexamer 4mut (S41A, Q67H, V165I, L172I)
Summary for 4XRO
Entry DOI | 10.2210/pdb4xro/pdb |
Descriptor | Capsid protein p24 (2 entities in total) |
Functional Keywords | viral protein, capsid |
Biological source | Human immunodeficiency virus type 1 group M subtype B (isolate NY5) (HIV-1) |
Cellular location | Gag polyprotein: Host cell membrane; Lipid- anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion : P12493 |
Total number of polymer chains | 1 |
Total formula weight | 25469.32 |
Authors | Price, A.J.,James, L.C. (deposition date: 2015-01-21, release date: 2015-07-15, Last modification date: 2024-01-10) |
Primary citation | Zhou, J.,Price, A.J.,Halambage, U.D.,James, L.C.,Aiken, C. HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry. J.Virol., 89:9068-9079, 2015 Cited by PubMed: 26109731DOI: 10.1128/JVI.00340-15 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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