4XDH
Crystal Structure of Quinone Reductase II in complex with a 2-(4-methoxy-phenyl)-5-methoxy-indol-3-one molecule
Summary for 4XDH
Entry DOI | 10.2210/pdb4xdh/pdb |
Descriptor | Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (6 entities in total) |
Functional Keywords | qr2, fad, flavoprotein, metal-binding, oxidoreductase, indolone oxide |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm: P16083 |
Total number of polymer chains | 2 |
Total formula weight | 54485.73 |
Authors | Sirigu, S.,Nepveu, F.,Vuillard, L.,Ferry, G.,Isabet, T.,Thompson, A.,Boutin, J.A. (deposition date: 2014-12-19, release date: 2016-01-13, Last modification date: 2024-05-08) |
Primary citation | Cassagnes, L.E.,Rakotoarivelo, N.,Sirigu, S.,Perio, P.,Najahi, E.,Chavas, L.M.,Thompson, A.,Gayon, R.,Ferry, G.,Boutin, J.A.,Valentin, A.,Reybier, K.,Nepveu, F. Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives. Molecules, 22:-, 2017 Cited by PubMed: 28146103DOI: 10.3390/molecules22020210 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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