4X50

Crystal structure of FimH in complex with biphenyl alpha-D-mannopyranoside

Summary for 4X50

• Entry DOI: 10.2210/pdb4x50/pdb
• Related: 4CSS 4CST
• Descriptor: Protein FimH, biphenyl-4-yl alpha-D-mannopyranoside (3 entities in total)
• Functional Keywords: sugar binding protein, bacterial adhesin, pilus, upec, antagonist complex
• Biological source: Escherichia coli K-12
• Cellular location: Fimbrium: P08191
• Total number of polymer chains: 2
• Total formula weight: 34838.77

Authors

Preston, R.C.,Jakob, R.P.,Fiege, B.,Zihlmann, P.,Rabbani, S.,Schwardt, O.,Jiang, X.,Ernst, B.,Maier, T. (deposition date: 2014-12-04, release date: 2015-05-20, Last modification date: 2024-01-10)

• Primary citation: Fiege, B.,Rabbani, S.,Preston, R.C.,Jakob, R.P.,Zihlmann, P.,Schwardt, O.,Jiang, X.,Maier, T.,Ernst, B.; The Tyrosine Gate of the Bacterial Lectin FimH: A Conformational Analysis by NMR Spectroscopy and X-ray Crystallography.; Chembiochem, 16:1235-1246, 2015; PubMed: 25940742; DOI: 10.1002/cbic.201402714

Experimental method

X-RAY DIFFRACTION (2 Å)