4WZ3

Crystal structure of the complex between LubX/LegU2/Lpp2887 U-box 1 and Homo sapiens UBE2D2

Summary for 4WZ3

Entry DOI	10.2210/pdb4wz3/pdb
Related	4WZ0 4WZ1 4WZ2
Descriptor	Ubiquitin-conjugating enzyme E2 D2, E3 ubiquitin-protein ligase LubX (3 entities in total)
Functional Keywords	alpha/beta protein, effector, activating enzyme, structural genomics, psi-biology, midwest center for structural genomics, mcsg, ligase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	41614.31
Authors	Stogios, P.J.,Quaile, A.T.,Skarina, T.,Nocek, B.,Di Leo, R.,Yim, V.,Savchenko, A.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG) (deposition date: 2014-11-18, release date: 2015-01-07, Last modification date: 2023-11-15)
Primary citation	Quaile, A.T.,Urbanus, M.L.,Stogios, P.J.,Nocek, B.,Skarina, T.,Ensminger, A.W.,Savchenko, A. Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila. Structure, 23:1459-1469, 2015 Cited by PubMed: 26146184 DOI: 10.1016/j.str.2015.05.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation