4WS8
Crystal structure of Mycobacterium tuberculosis uracil-DNA glycosylase in complex with 2-thiouracil, Form V
Summary for 4WS8
Entry DOI | 10.2210/pdb4ws8/pdb |
Related | 4WRU 4WRV 4WRW 4WRX 4WRY 4WRZ 4WS0 4WS1 4WS2 4WS3 4WS4 4WS5 4WS6 4WS7 |
Descriptor | Uracil-DNA glycosylase, 2-thioxo-2,3-dihydropyrimidin-4(1H)-one, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | dna-repair, excision repair, conformational selection, ligand-binding, hydrolase |
Biological source | Mycobacterium tuberculosis |
Cellular location | Cytoplasm : P9WFQ9 |
Total number of polymer chains | 1 |
Total formula weight | 25977.15 |
Authors | Arif, S.M.,Geethanandan, K.,Mishra, P.,Surolia, A.,Varshney, U.,Vijayan, M. (deposition date: 2014-10-25, release date: 2015-07-15, Last modification date: 2023-09-27) |
Primary citation | Arif, S.M.,Geethanandan, K.,Mishra, P.,Surolia, A.,Varshney, U.,Vijayan, M. Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implications. Acta Crystallogr.,Sect.D, 71:1514-1527, 2015 Cited by PubMed: 26143923DOI: 10.1107/S1399004715009311 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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