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4WF1

Crystal structure of the E. coli ribosome bound to negamycin.

This is a non-PDB format compatible entry.
Summary for 4WF1
Entry DOI10.2210/pdb4wf1/pdb
Descriptor16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (57 entities in total)
Functional Keywordsprotein biosynthesis, ribosomes, rna, transfer, exit, peptidyl, 30s, 70s, 16s, ribosomal subunit, antibiotic, streptogramin, ribosome-antibiotic complex, ribosome/antibiotic
Biological sourceEscherichia coli str. K-12 substr. MG1655
More
Total number of polymer chains105
Total formula weight4265689.91
Authors
Primary citationOlivier, N.B.,Altman, R.B.,Noeske, J.,Basarab, G.S.,Code, E.,Ferguson, A.D.,Gao, N.,Huang, J.,Juette, M.F.,Livchak, S.,Miller, M.D.,Prince, D.B.,Cate, J.H.,Buurman, E.T.,Blanchard, S.C.
Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
Proc.Natl.Acad.Sci.USA, 111:16274-16279, 2014
Cited by
PubMed: 25368144
DOI: 10.1073/pnas.1414401111
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.09 Å)
Structure validation

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