4WF1
Crystal structure of the E. coli ribosome bound to negamycin.
This is a non-PDB format compatible entry.
Summary for 4WF1
Entry DOI | 10.2210/pdb4wf1/pdb |
Descriptor | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (57 entities in total) |
Functional Keywords | protein biosynthesis, ribosomes, rna, transfer, exit, peptidyl, 30s, 70s, 16s, ribosomal subunit, antibiotic, streptogramin, ribosome-antibiotic complex, ribosome/antibiotic |
Biological source | Escherichia coli str. K-12 substr. MG1655 More |
Total number of polymer chains | 105 |
Total formula weight | 4265689.91 |
Authors | Olivier, N.B.,Altman, R.B.,Noeske, J.,Basarab, G.S.,Code, E.,Ferguson, A.D.,Gao, N.,Huang, J.,Juette, M.F.,Livchak, S.,Miller, M.D.,Prince, D.B.,Cate, J.H.D.,Buurman, E.T.,Blanchard, S.C. (deposition date: 2014-09-11, release date: 2014-11-05, Last modification date: 2024-10-16) |
Primary citation | Olivier, N.B.,Altman, R.B.,Noeske, J.,Basarab, G.S.,Code, E.,Ferguson, A.D.,Gao, N.,Huang, J.,Juette, M.F.,Livchak, S.,Miller, M.D.,Prince, D.B.,Cate, J.H.,Buurman, E.T.,Blanchard, S.C. Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome. Proc.Natl.Acad.Sci.USA, 111:16274-16279, 2014 Cited by PubMed: 25368144DOI: 10.1073/pnas.1414401111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.09 Å) |
Structure validation
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