4UU5

CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1 IN COMPLEX WITH THE CRB PEPTIDE

Summary for 4UU5

• Entry DOI: 10.2210/pdb4uu5/pdb
• Related: 4UU6
• Descriptor: MAGUK P55 SUBFAMILY MEMBER 5, PROTEIN CRUMBS HOMOLOG 1, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: cell adhesion
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cell membrane; Peripheral membrane protein: Q8N3R9; Isoform 1: Apical cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P82279
• Total number of polymer chains: 2
• Total formula weight: 12284.67

Authors

Ivanova, M.E.,Purkiss, A.G.,McDonald, N.Q. (deposition date: 2014-07-24, release date: 2015-01-14, Last modification date: 2024-01-10)

• Primary citation: Ivanova, M.E.,Fletcher, G.C.,O'Reilly, N.,Purkiss, A.G.,Thompson, B.J.,McDonald, N.Q.; Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove.; Acta Crystallogr. D Biol. Crystallogr., 71:555-564, 2015; PubMed: 25760605; DOI: 10.1107/S139900471402776X

Experimental method

X-RAY DIFFRACTION (1.23 Å)