4UFJ
Mouse Galactocerebrosidase complexed with iso-galacto-fagomine lactam IGL
Summary for 4UFJ
Entry DOI | 10.2210/pdb4ufj/pdb |
Related | 4UFH 4UFI 4UFK 4UFL 4UFM |
Descriptor | GALACTOCEREBROSIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, (3S,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)piperidin-2-one, ... (6 entities in total) |
Functional Keywords | hydrolase, glycosyl hydrolase, complex, lysosome |
Biological source | MUS MUSCULUS (HOUSE MOUSE) |
Cellular location | Lysosome : P54818 |
Total number of polymer chains | 1 |
Total formula weight | 76292.39 |
Authors | Hill, C.H.,Viuff, A.H.,Spratley, S.J.,Salamone, S.,Christensen, S.H.,Read, R.J.,Moriarty, N.W.,Jensen, H.H.,Deane, J.E. (deposition date: 2015-03-17, release date: 2015-03-25, Last modification date: 2023-12-20) |
Primary citation | Hill, C.H.,Viuff, A.H.,Spratley, S.J.,Salamone, S.,Christensen, S.H.,Read, R.J.,Moriarty, N.W.,Jensen, H.H.,Deane, J.E. Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease. Chem.Sci., 6:3075-, 2015 Cited by PubMed: 26029356DOI: 10.1039/C5SC00754B PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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