4UBD

Crystal structure of a neutralizing human monoclonal antibody with 1968 H3 HA

Summary for 4UBD

• Entry DOI: 10.2210/pdb4ubd/pdb
• Descriptor: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, monoclonal antibody H chain, ... (7 entities in total)
• Functional Keywords: hemagglutinin, h3n2, monoclonal antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus; More
• Total number of polymer chains: 24
• Total formula weight: 625697.69

Authors

Shore, D.A.,Yang, H.,Cho, M.,Donis, R.O.,Stevens, J. (deposition date: 2014-08-12, release date: 2015-06-24, Last modification date: 2023-12-27)

• Primary citation: Wu, Y.,Cho, M.,Shore, D.,Song, M.,Choi, J.,Jiang, T.,Deng, Y.Q.,Bourgeois, M.,Almli, L.,Yang, H.,Chen, L.M.,Shi, Y.,Qi, J.,Li, A.,Yi, K.S.,Chang, M.,Bae, J.S.,Lee, H.,Shin, J.,Stevens, J.,Hong, S.,Qin, C.F.,Gao, G.F.,Chang, S.J.,Donis, R.O.; A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus.; Nat Commun, 6:7708-7708, 2015; PubMed: 26196962; DOI: 10.1038/ncomms8708

Experimental method

X-RAY DIFFRACTION (3.5 Å)