4UAM

1.8 Angstrom crystal structure of IMP-1 metallo-beta-lactamase with a mixed iron-zinc center in the active site

Summary for 4UAM

• Entry DOI: 10.2210/pdb4uam/pdb
• Descriptor: IMP-1 metallo-beta-lactamase, FE (III) ION, ZINC ION, ... (5 entities in total)
• Functional Keywords: antibiotic resistance, binuclear metal center, hydrolase
• Biological source: Pseudomonas aeruginosa NCGM2.S1
• Total number of polymer chains: 4
• Total formula weight: 101828.12

Authors

Carruthers, T.J.,Carr, P.D.,Jackson, C.J.,Otting, G. (deposition date: 2014-08-11, release date: 2014-09-17, Last modification date: 2023-09-27)

• Primary citation: Carruthers, T.J.,Carr, P.D.,Loh, C.T.,Jackson, C.J.,Otting, G.; Iron(III) Located in the Dinuclear Metallo-beta-Lactamase IMP-1 by Pseudocontact Shifts.; Angew.Chem.Int.Ed.Engl., 53:14269-14272, 2014; PubMed: 25320022; DOI: 10.1002/anie.201408693

Experimental method

X-RAY DIFFRACTION (1.8 Å)