4U2V

Bak BH3-in-Groove dimer (GFP)

Summary for 4U2V

• Entry DOI: 10.2210/pdb4u2v/pdb
• Related: 4U2U
• Descriptor: Green fluorescent protein,Bcl-2 homologous antagonist/killer, CACODYLATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: apoptosis, bak, bcl-2
• Biological source: Aequorea victoria (Jellyfish); More
• Total number of polymer chains: 4
• Total formula weight: 142741.37

Authors

Brouwer, J.M.,Colman, P.M.,Czabotar, P.E. (deposition date: 2014-07-18, release date: 2014-09-10, Last modification date: 2023-11-15)

• Primary citation: Brouwer, J.M.,Westphal, D.,Dewson, G.,Robin, A.Y.,Uren, R.T.,Bartolo, R.,Thompson, G.V.,Colman, P.M.,Kluck, R.M.,Czabotar, P.E.; Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers.; Mol.Cell, 55:938-946, 2014; PubMed: 25175025; DOI: 10.1016/j.molcel.2014.07.016

Experimental method

X-RAY DIFFRACTION (2.3 Å)