4U0F
Hexameric HIV-1 CA in Complex with BI-2
Summary for 4U0F
Entry DOI | 10.2210/pdb4u0f/pdb |
Related | 4U0A 4U0B 4U0C 4U0D 4U0E |
Descriptor | Capsid protein p24, 1,2-ETHANEDIOL, (4S)-4-(4-hydroxyphenyl)-3-phenyl-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one, ... (4 entities in total) |
Functional Keywords | capsid, inhibitor, viral protein |
Biological source | Human immunodeficiency virus type 1 group M subtype B (HIV-1) |
Cellular location | Gag polyprotein: Host cell membrane; Lipid- anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion : P12493 |
Total number of polymer chains | 1 |
Total formula weight | 25814.64 |
Authors | Price, A.J.,Jacques, D.A.,James, L.C. (deposition date: 2014-07-11, release date: 2014-11-12, Last modification date: 2023-12-20) |
Primary citation | Price, A.J.,Jacques, D.A.,McEwan, W.A.,Fletcher, A.J.,Essig, S.,Chin, J.W.,Halambage, U.D.,Aiken, C.,James, L.C. Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly. Plos Pathog., 10:e1004459-e1004459, 2014 Cited by PubMed: 25356722DOI: 10.1371/journal.ppat.1004459 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.22 Å) |
Structure validation
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