4RBY

First X-ray structure of RNA containing guanosine phosphorodithioate

Summary for 4RBY

• Entry DOI: 10.2210/pdb4rby/pdb
• Related: 4RBZ 4RC0
• Descriptor: 5'-R(*CP*GP*CP*(2SG)P*AP*AP*UP*UP*AP*GP*CP*G)-3', STRONTIUM ION (3 entities in total)
• Functional Keywords: phosphorodithioate rna, guanosine phosphorodithioate, phosphorothioate, guanosine analogue, hydrophobic, backbone, rna
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 4060.75

Authors

Pallan, P.S.,Egli, M. (deposition date: 2014-09-13, release date: 2015-09-16, Last modification date: 2023-09-20)

• Primary citation: Pallan, P.S.,Yang, X.,Sierant, M.,Abeydeera, N.D.,Hassell, T.,Martinez, C.,Janicka, M.,Nawrot, B.,Egli, M.; Crystal Structure, Stability and siRNA Activity of Phosphorodithioate-Modified RNAs; To be Published,

Experimental method

X-RAY DIFFRACTION (1.19 Å)