4R12
Crystal structure of the gamma-secretase component Nicastrin
Summary for 4R12
Entry DOI | 10.2210/pdb4r12/pdb |
Descriptor | Putative uncharacterized protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | alpha/beta, nicastrin, putative substrate-recruiting component, gamma-secretase complex, protein binding |
Biological source | Dictyostelium purpureum (Slime mold) |
Total number of polymer chains | 1 |
Total formula weight | 68440.68 |
Authors | |
Primary citation | Xie, T.,Yan, C.,Zhou, R.,Zhao, Y.,Sun, L.,Yang, G.,Lu, P.,Ma, D.,Shi, Y. Crystal structure of the gamma-secretase component nicastrin. Proc.Natl.Acad.Sci.USA, 111:13349-13354, 2014 Cited by PubMed: 25197054DOI: 10.1073/pnas.1414837111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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