4QPM
Structure of Bub1 kinase domain
Summary for 4QPM
Entry DOI | 10.2210/pdb4qpm/pdb |
Descriptor | Mitotic checkpoint serine/threonine-protein kinase BUB1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O43683 |
Total number of polymer chains | 2 |
Total formula weight | 83313.32 |
Authors | Lin, Z.H.,Jia, L.Y.,Tomchick, D.R.,Luo, X.L.,Yu, H.T. (deposition date: 2014-06-24, release date: 2014-10-22, Last modification date: 2014-12-24) |
Primary citation | Lin, Z.,Jia, L.,Tomchick, D.R.,Luo, X.,Yu, H. Substrate-Specific Activation of the Mitotic Kinase Bub1 through Intramolecular Autophosphorylation and Kinetochore Targeting. Structure, 22:1616-1627, 2014 Cited by PubMed: 25308863DOI: 10.1016/j.str.2014.08.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.202 Å) |
Structure validation
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