4QH9
Crystal structure of Mn2+ bound human APE1
Summary for 4QH9
| Entry DOI | 10.2210/pdb4qh9/pdb |
| Related | 4QHD 4QHE |
| Descriptor | DNA-(apurinic or apyrimidinic site) lyase, 1,2-ETHANEDIOL, MANGANESE (II) ION, ... (4 entities in total) |
| Functional Keywords | beta sandwich, endonuclease, dna-binding, nucleus, lyase |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus. DNA-(apurinic or apyrimidinic site) lyase, mitochondrial: Mitochondrion: P27695 |
| Total number of polymer chains | 1 |
| Total formula weight | 32500.79 |
| Authors | Chen, Q.,He, H.,Georgiadis, M.M. (deposition date: 2014-05-27, release date: 2014-11-12, Last modification date: 2024-02-28) |
| Primary citation | He, H.,Chen, Q.,Georgiadis, M.M. High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I. Biochemistry, 53:6520-6529, 2014 Cited by PubMed: 25251148DOI: 10.1021/bi500676p PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.175 Å) |
Structure validation
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