4QCK

Crystal structure of 3-ketosteroid-9-alpha-hydroxylase (KshA) from M. tuberculosis in complex with 4-androstene-3,17-dione

Summary for 4QCK

• Entry DOI: 10.2210/pdb4qck/pdb
• Related: 4QDC 4QDD 4QDF
• Descriptor: 3-ketosteroid-9-alpha-monooxygenase oxygenase subunit, FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, ... (6 entities in total)
• Functional Keywords: mixed function oxygenases, oxidoreductase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 44939.51

Authors

Penfield, J.,Worrall, L.J.,Strynadka, N.C.,Eltis, L.D. (deposition date: 2014-05-12, release date: 2014-07-30, Last modification date: 2024-02-28)

• Primary citation: Penfield, J.S.,Worrall, L.J.,Strynadka, N.C.,Eltis, L.D.; Substrate specificities and conformational flexibility of 3-ketosteroid 9 alpha-hydroxylases.; J.Biol.Chem., 289:25523-25536, 2014; PubMed: 25049233; DOI: 10.1074/jbc.M114.575886

Experimental method

X-RAY DIFFRACTION (2.46 Å)