4PXT
Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers
Summary for 4PXT
| Entry DOI | 10.2210/pdb4pxt/pdb |
| Related | 4PXU |
| Descriptor | Bipolar kinesin KRP-130 (1 entity in total) |
| Functional Keywords | coiled-coil, bipolar assembly domain of kinesin-5, bipolar tetramers, anti-parallel four-helix bundle, kinesin-5 functions via a "sliding filament" mechanism, crosslinking adjacent microtubules into bundles throughout the mitotic spindle, microtubules, cell cycle |
| Biological source | Drosophila melanogaster (Fruit fly) |
| Total number of polymer chains | 2 |
| Total formula weight | 49967.44 |
| Authors | Scholey, J.E.,Nithianantham, S.,Scholey, J.M.,Al-Bassam, J. (deposition date: 2014-03-25, release date: 2014-04-23) |
| Primary citation | Scholey, J.E.,Nithianantham, S.,Scholey, J.M.,Al-Bassam, J. Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers. Elife, 3:e02217-e02217, 2014 Cited by PubMed: 24714498PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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