4PVM

Neutron structure of human transthyretin (TTR) at room temperature to 2.0A resolution (Laue)

Summary for 4PVM

Entry DOI	10.2210/pdb4pvm/pdb
Related	2PAB 3IPE 3U2I 4PVL 4PVN
Descriptor	Transthyretin (2 entities in total)
Functional Keywords	beta sandwich, transport protein, serum
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02766
Total number of polymer chains	2
Total formula weight	28073.38
Authors	Fisher, S.J.,Blakeley, M.P.,Haupt, M.,Mason, S.A.,Cooper, J.B.,Mitchell, E.P.,Forsyth, V.T. (deposition date: 2014-03-18, release date: 2014-11-12, Last modification date: 2024-03-20)
Primary citation	Haupt, M.,Blakeley, M.P.,Fisher, S.J.,Mason, S.A.,Cooper, J.B.,Mitchell, E.P.,Forsyth, V.T. Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein IUCrJ, 1:429-438, 2014 Cited by PubMed: 25485123 DOI: 10.1107/S2052252514021113 PDB entries with the same primary citation
Experimental method	NEUTRON DIFFRACTION (2 Å) X-RAY DIFFRACTION (1.95 Å)

Structure validation