4PGT

CRYSTAL STRUCTURE OF HGSTP1-1[V104] COMPLEXED WITH THE GSH CONJUGATE OF (+)-ANTI-BPDE

Summary for 4PGT

Entry DOI	10.2210/pdb4pgt/pdb
Related	1PGT 2PGT 3PGT
Descriptor	PROTEIN (GLUTATHIONE S-TRANSFERASE), SULFATE ION, 2-AMINO-4-[1-(CARBOXYMETHYL-CARBAMOYL)-2-(9-HYDROXY-7,8-DIOXO-7,8,9,10-TETRAHYDRO-BENZO[DEF]CHRYSEN-10-YLSULFANYL)-ETHYLCARBAMOYL]-BUTYRIC ACID, ... (5 entities in total)
Functional Keywords	transferase, pi class, hgstp1-1[v104], detoxification
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	48553.31
Authors	Ji, X.,Blaszczyk, J. (deposition date: 1999-03-22, release date: 1999-09-01, Last modification date: 2023-11-15)
Primary citation	Ji, X.,Blaszczyk, J.,Xiao, B.,O'Donnell, R.,Hu, X.,Herzog, C.,Singh, S.V.,Zimniak, P. Structure and function of residue 104 and water molecules in the xenobiotic substrate-binding site in human glutathione S-transferase P1-1. Biochemistry, 38:10231-10238, 1999 Cited by PubMed: 10441116 DOI: 10.1021/bi990668u PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation