4PBX
Crystal structure of the six N-terminal domains of human receptor protein tyrosine phosphatase sigma
Summary for 4PBX
Entry DOI | 10.2210/pdb4pbx/pdb |
Related | 2YD2 2YD3 2YD9 |
Descriptor | Receptor-type tyrosine-protein phosphatase S, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total) |
Functional Keywords | signaling protein, synapse cell signalling cell surface receptor, hydrolase |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane ; Single-pass type I membrane protein : Q13332 |
Total number of polymer chains | 1 |
Total formula weight | 64786.45 |
Authors | Coles, C.H.,Mitakidis, N.,Zhang, P.,Elegheert, J.,Lu, W.,Stoker, A.W.,Nakagawa, T.,Craig, A.M.,Jones, E.Y.,Aricescu, A.R. (deposition date: 2014-04-14, release date: 2014-11-12, Last modification date: 2023-12-20) |
Primary citation | Coles, C.H.,Mitakidis, N.,Zhang, P.,Elegheert, J.,Lu, W.,Stoker, A.W.,Nakagawa, T.,Craig, A.M.,Jones, E.Y.,Aricescu, A.R. Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis. Nat Commun, 5:5209-5209, 2014 Cited by PubMed: 25385546DOI: 10.1038/ncomms6209 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.15 Å) |
Structure validation
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