4NQV

Crystal Structure of HLA A*0101 in complex with NP44, an 9-mer influenza epitope

Summary for 4NQV

• Entry DOI: 10.2210/pdb4nqv/pdb
• Related: 4NQX
• Descriptor: HLA class I histocompatibility antigen, A-1 alpha chain, Beta-2-microglobulin, Nucleoprotein, ... (4 entities in total)
• Functional Keywords: immune system, hla presenting h7n9 viral epitope, t cell receptor, immune system-viral protein complex, immune system/viral protein
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P30443; Secreted: P61769
• Total number of polymer chains: 18
• Total formula weight: 267531.13

Authors

Rossjohn, J.,Gras, S. (deposition date: 2013-11-25, release date: 2013-12-25, Last modification date: 2023-09-20)

• Primary citation: Quinones-Parra, S.,Grant, E.,Loh, L.,Nguyen, T.H.,Campbell, K.A.,Tong, S.Y.,Miller, A.,Doherty, P.C.,Vijaykrishna, D.,Rossjohn, J.,Gras, S.,Kedzierska, K.; Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities.; Proc.Natl.Acad.Sci.USA, 111:1049-1054, 2014; PubMed: 24395804; DOI: 10.1073/pnas.1322229111

Experimental method

X-RAY DIFFRACTION (2.39 Å)