4NNX

Crystal structure of PKD2 phosphopeptide bound to HLA-A2

Summary for 4NNX

Entry DOI	10.2210/pdb4nnx/pdb
Related	4NNY 4NO0 4NO2 4NO3 4NO5
Descriptor	HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Serine/threonine-protein kinase D2, ... (6 entities in total)
Functional Keywords	phosphoserine, phosphopeptide, mhc, post translational modification, tumor immunology, tumor antigens, neoepitope, immune system-antigen complex, immune system/antigen
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	45056.06
Authors	Mohammed, F.,Stones, D.H.,Willcox, B.E. (deposition date: 2013-11-19, release date: 2014-11-19, Last modification date: 2023-09-20)
Primary citation	Mohammed, F.,Stones, D.H.,Zarling, A.L.,Willcox, C.R.,Shabanowitz, J.,Cummings, K.L.,Hunt, D.F.,Cobbold, M.,Engelhard, V.H.,Willcox, B.E. The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status. Oncotarget, 8:54160-54172, 2017 Cited by PubMed: 28903331 DOI: 10.18632/oncotarget.16952 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.104 Å)

Structure validation