4MUB

Schistosoma mansoni (Blood Fluke) Sulfotransferase/Oxamniquine Complex

Summary for 4MUB

• Entry DOI: 10.2210/pdb4mub/pdb
• Descriptor: Sulfotransferase, ADENOSINE-3'-5'-DIPHOSPHATE, {(2S)-7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl}methanol, ... (4 entities in total)
• Functional Keywords: pap, oxamniquine, parasite, helminth, drug resistance, transferase
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 1
• Total formula weight: 30683.10

Authors

Valentim, C.L.L.,Cioli, D.,Chevalier, F.D.,Cao, X.,Taylor, A.B.,Holloway, S.P.,Pica-Mattoccia, L.,Guidi, A.,Basso, A.,Tsai, I.J.,Berriman, M.,Carvalho-Queiroz, C.,Almeida, M.,Aguilar, H.,Frantz, D.E.,Hart, P.J.,Anderson, T.J.C.,LoVerde, P.T. (deposition date: 2013-09-21, release date: 2013-12-18, Last modification date: 2024-02-28)

• Primary citation: Valentim, C.L.,Cioli, D.,Chevalier, F.D.,Cao, X.,Taylor, A.B.,Holloway, S.P.,Pica-Mattoccia, L.,Guidi, A.,Basso, A.,Tsai, I.J.,Berriman, M.,Carvalho-Queiroz, C.,Almeida, M.,Aguilar, H.,Frantz, D.E.,Hart, P.J.,LoVerde, P.T.,Anderson, T.J.; Genetic and molecular basis of drug resistance and species-specific drug action in schistosome parasites.; Science, 342:1385-1389, 2013; PubMed: 24263136; DOI: 10.1126/science.1243106

Experimental method

X-RAY DIFFRACTION (1.75 Å)