4M0E
Structure of human acetylcholinesterase in complex with dihydrotanshinone I
Summary for 4M0E
Entry DOI | 10.2210/pdb4m0e/pdb |
Related | 4M0F |
Descriptor | Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Dihydrotanshinone I, ... (7 entities in total) |
Functional Keywords | acetylcholinesterase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 121123.32 |
Authors | Cheung, J.,Gary, E.N.,Shiomi, K.,Rosenberry, T.L. (deposition date: 2013-08-01, release date: 2013-10-16, Last modification date: 2023-09-20) |
Primary citation | Cheung, J.,Gary, E.N.,Shiomi, K.,Rosenberry, T.L. Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility. ACS Med Chem Lett, 4:1091-1096, 2013 Cited by PubMed: 24900610DOI: 10.1021/ml400304w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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