4KYK

Crystal structure of mouse glyoxalase I complexed with indomethacin

Summary for 4KYK

• Entry DOI: 10.2210/pdb4kyk/pdb
• Related: 2ZA0 4KYH
• Descriptor: Lactoylglutathione lyase, ZINC ION, INDOMETHACIN, ... (4 entities in total)
• Functional Keywords: lactoylglutachione lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Mus musculus (mouse)
• Total number of polymer chains: 2
• Total formula weight: 42159.77

Authors

Zhai, J.,Yuan, M.,Zhang, L.,Chen, Y.,Zhang, H.,Chen, S.,Zhao, Y. (deposition date: 2013-05-29, release date: 2013-08-07, Last modification date: 2022-08-24)

• Primary citation: Zhai, J.,Zhang, H.,Zhang, L.,Zhao, Y.,Chen, S.,Chen, Y.,Peng, X.,Li, Q.,Yuan, M.,Hu, X.; Zopolrestat as a human glyoxalase I inhibitor and its structural basis.; Chemmedchem, 8:1462-1464, 2013; PubMed: 23857942; DOI: 10.1002/cmdc.201300243

Experimental method

X-RAY DIFFRACTION (2 Å)