4KTE
Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE148, from non-human primate
Summary for 4KTE
Entry DOI | 10.2210/pdb4kte/pdb |
Related | 4KTD |
Descriptor | GE148 Heavy Chain Fab, GE148 Light Chain Fab, SULFATE ION, ... (5 entities in total) |
Functional Keywords | antibody affinity, antibody specificity, vaccine elicited antibodies, fab fragment, aids vaccines, immune system |
Biological source | Macaca mulatta (rhesus macaque) More |
Total number of polymer chains | 2 |
Total formula weight | 48831.35 |
Authors | Poulsen, C.,Tran, K.,Stanfield, R.,Wyatt, R.T. (deposition date: 2013-05-20, release date: 2014-02-05, Last modification date: 2019-12-25) |
Primary citation | Tran, K.,Poulsen, C.,Guenaga, J.,de Val Alda, N.,Wilson, R.,Sundling, C.,Li, Y.,Stanfield, R.L.,Wilson, I.A.,Ward, A.B.,Karlsson Hedestam, G.B.,Wyatt, R.T. Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign. Proc.Natl.Acad.Sci.USA, 111:E738-E747, 2014 Cited by PubMed: 24550318DOI: 10.1073/pnas.1319512111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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