4KSY

Crystal structure of STING in complex with cGAMP

Summary for 4KSY

• Entry DOI: 10.2210/pdb4ksy/pdb
• Descriptor: Stimulator of interferon genes protein, cGAMP (3 entities in total)
• Functional Keywords: innate immunity, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 27855.06

Authors

Zhang, X.,Chen, Z.J.,Zhang, X.W. (deposition date: 2013-05-18, release date: 2013-06-12, Last modification date: 2024-02-28)

• Primary citation: Zhang, X.,Shi, H.,Wu, J.,Zhang, X.,Sun, L.,Chen, C.,Chen, Z.J.; Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING.; Mol.Cell, 51:226-235, 2013; PubMed: 23747010; DOI: 10.1016/j.molcel.2013.05.022

Experimental method

X-RAY DIFFRACTION (1.881 Å)