4K2F

Structure of Pseudomonas aeruginosa PvdQ bound to BRD-A08522488

Summary for 4K2F

Entry DOI	10.2210/pdb4k2f/pdb
Related	3SRA 3SRB 3SRC 4K2G
Descriptor	Acyl-homoserine lactone acylase PvdQ, 1,2-ETHANEDIOL, (2S)-(4-chlorophenyl)(6-chloropyridin-2-yl)ethanenitrile, ... (5 entities in total)
Functional Keywords	amidohydrolase, bacterial protein, catalytic domain, high-throughput screening assays, molecular sequence data, oligopeptides, small molecule libraries, structure-activity relationship, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Pseudomonas aeruginosa More
Cellular location	Periplasm (Probable): Q9I194 Q9I194
Total number of polymer chains	2
Total formula weight	79966.64
Authors	Drake, E.J.,Wurst, J.M.,Theriault, J.R.,Munoz, B.,Gulick, A.M. (deposition date: 2013-04-09, release date: 2014-06-18, Last modification date: 2023-09-20)
Primary citation	Wurst, J.M.,Drake, E.J.,Theriault, J.R.,Jewett, I.T.,VerPlank, L.,Perez, J.R.,Dandapani, S.,Palmer, M.,Moskowitz, S.M.,Schreiber, S.L.,Munoz, B.,Gulick, A.M. Identification of Inhibitors of PvdQ, an Enzyme Involved in the Synthesis of the Siderophore Pyoverdine. Acs Chem.Biol., 9:1536-1544, 2014 Cited by PubMed: 24824984 DOI: 10.1021/cb5001586 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation