4JSD
The X-ray crystal structure of a thermophilic cellobiose binding protein bound with laminaribiose
Summary for 4JSD
| Entry DOI | 10.2210/pdb4jsd/pdb |
| Related | 2O7I 3I5O 4JSO |
| Related PRD ID | PRD_900024 |
| Descriptor | Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, CALCIUM ION, ... (4 entities in total) |
| Functional Keywords | periplasmic binding protein, thermophilic protein, cellulose, sugar binding protein, cellobiose binding protein |
| Biological source | Thermotoga maritima |
| Total number of polymer chains | 1 |
| Total formula weight | 67792.46 |
| Authors | Munshi, P.,Cuneo, M.J. (deposition date: 2013-03-22, release date: 2013-10-09, Last modification date: 2023-09-20) |
| Primary citation | Munshi, P.,Stanley, C.B.,Ghimire-Rijal, S.,Lu, X.,Myles, D.A.,Cuneo, M.J. Molecular details of ligand selectivity determinants in a promiscuous beta-glucan periplasmic binding protein. Bmc Struct.Biol., 13:18-18, 2013 Cited by PubMed Abstract: Members of the periplasmic binding protein (PBP) superfamily utilize a highly conserved inter-domain ligand binding site that adapts to specifically bind a chemically diverse range of ligands. This paradigm of PBP ligand binding specificity was recently altered when the structure of the Thermotoga maritima cellobiose-binding protein (tmCBP) was solved. The tmCBP binding site is bipartite, comprising a canonical solvent-excluded region (subsite one), adjacent to a solvent-filled cavity (subsite two) where specific and semi-specific ligand recognition occur, respectively. PubMed: 24090243DOI: 10.1186/1472-6807-13-18 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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