4JFW

Crystal structure of a bacterial fucosidase with iminosugar inhibitor (2S,3S,4R,5S)-2-[N-(propylferrocene)]aminoethyl-5-methylpyrrolidine-3,4-diol

Summary for 4JFW

Entry DOI	10.2210/pdb4jfw/pdb
Related	2WVV 4J27 4J28 4JFS 4JFT 4JFU 4JFV
Descriptor	alpha-L-fucosidase, (3alpha)-[3-({2-[(2S,3S,4R,5S)-3,4-dihydroxy-5-methylpyrrolidin-2-yl]ethyl}amino)propyl]ferrocene, SULFATE ION, ... (5 entities in total)
Functional Keywords	alpha-l-fucosidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bacteroides thetaiotaomicron
Total number of polymer chains	4
Total formula weight	210817.74
Authors	Wright, D.W.,Davies, G.J. (deposition date: 2013-02-28, release date: 2013-09-18, Last modification date: 2023-09-20)
Primary citation	Hottin, A.,Wright, D.W.,Steenackers, A.,Delannoy, P.,Dubar, F.,Biot, C.,Davies, G.J.,Behr, J.B. alpha-L-fucosidase inhibition by pyrrolidine-ferrocene hybrids: rationalization of ligand-binding properties by structural studies. Chemistry, 19:9526-9533, 2013 Cited by PubMed: 23740878 DOI: 10.1002/chem.201301001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation