4JDW
CRYSTAL STRUCTURE AND MECHANISM OF L-ARGININE: GLYCINE AMIDINOTRANSFERASE: A MITOCHONDRIAL ENZYME INVOLVED IN CREATINE BIOSYNTHESIS
Summary for 4JDW
Entry DOI | 10.2210/pdb4jdw/pdb |
Descriptor | L-ARGININE\:GLYCINE AMIDINOTRANSFERASE, ARGININE (3 entities in total) |
Functional Keywords | transferase, creatine biosynthesis, catalytic triad, reaction mechanism, novel fold, fivefold pseudosymmetry |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side (Potential): P50440 |
Total number of polymer chains | 1 |
Total formula weight | 48664.51 |
Authors | Humm, A.,Fritsche, E.,Steinbacher, S.,Huber, R. (deposition date: 1997-01-24, release date: 1998-01-28, Last modification date: 2024-05-22) |
Primary citation | Humm, A.,Fritsche, E.,Steinbacher, S.,Huber, R. Crystal structure and mechanism of human L-arginine:glycine amidinotransferase: a mitochondrial enzyme involved in creatine biosynthesis. EMBO J., 16:3373-3385, 1997 Cited by PubMed: 9218780DOI: 10.1093/emboj/16.12.3373 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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