4ITX

P113S mutant of E. coli Cystathionine beta-lyase MetC inhibited by reaction with L-Ala-P

Summary for 4ITX

• Entry DOI: 10.2210/pdb4itx/pdb
• Related: 4ITG
• Descriptor: Cystathionine beta-lyase MetC, {1-[(3-HYDROXY-METHYL-5-PHOSPHONOOXY-METHYL-PYRIDIN-4-YLMETHYL)-AMINO]-ETHYL}-PHOSPHONIC ACID, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: cystathionine beta-lyase, lyase
• Biological source: Escherichia coli
• Cellular location: Cytoplasm: P06721
• Total number of polymer chains: 2
• Total formula weight: 87295.04

Authors

Squire, C.J.,Yosaatmadja, Y.,Soo, V.W.C.,Patrick, W.M. (deposition date: 2013-01-19, release date: 2014-12-24, Last modification date: 2023-09-20)

• Primary citation: Soo, V.W.,Yosaatmadja, Y.,Squire, C.J.,Patrick, W.M.; Mechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes.; J.Biol.Chem., 291:19873-19887, 2016; PubMed: 27474741; DOI: 10.1074/jbc.M116.739557

Experimental method

X-RAY DIFFRACTION (1.61 Å)