4INQ

Crystal structure of Osh3 ORD in complex with PI(4)P from Saccharomyces cerevisiae

Summary for 4INQ

• Entry DOI: 10.2210/pdb4inq/pdb
• Related: 4IAP 4IC4
• Descriptor: Oxysterol-binding protein homolog 3, (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate (3 entities in total)
• Functional Keywords: beta barrel, lipid transport, pi(4)p, lipid binding protein
• Biological source: Saccharomyces cerevisiae (Baker's yeast)
• Cellular location: Cytoplasm: P38713
• Total number of polymer chains: 1
• Total formula weight: 46350.29

Authors

Tong, J.,Im, Y.J. (deposition date: 2013-01-05, release date: 2013-07-31, Last modification date: 2023-11-08)

• Primary citation: Tong, J.,Yang, H.,Yang, H.,Eom, S.H.,Im, Y.J.; Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins; Structure, 21:1203-1213, 2013; PubMed: 23791945; DOI: 10.1016/j.str.2013.05.007

Experimental method

X-RAY DIFFRACTION (2.2 Å)