4IJ2

Human methemoglobin in complex with the second and third NEAT domains of IsdH from Staphylococcus aureus

Summary for 4IJ2

Entry DOI	10.2210/pdb4ij2/pdb
Related	4FC3
Descriptor	Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein H, ... (4 entities in total)
Functional Keywords	neat, heme/hemoglobin binding, hemoglobin, cell wall associated, oxygen transport-protein binding complex, oxygen transport/protein binding
Biological source	Staphylococcus aureus More
Cellular location	Secreted, cell wall ; Peptidoglycan-anchor : Q2FG07
Total number of polymer chains	8
Total formula weight	219896.27
Authors	Dickson, C.F.,Jacques, D.A.,Guss, J.M.,Gell, D.A. (deposition date: 2012-12-21, release date: 2013-12-25, Last modification date: 2023-11-08)
Primary citation	Dickson, C.F.,Krishna Kumar, K.,Jacques, D.A.,Malmirchegini, G.R.,Spirig, T.,Mackay, J.P.,Clubb, R.T.,Guss, J.M.,Gell, D.A. Structure of the Hemoglobin-IsdH Complex Reveals the Molecular Basis of Iron Capture by Staphylococcus aureus J.Biol.Chem., 289:6728-6738, 2014 Cited by PubMed: 24425866 DOI: 10.1074/jbc.M113.545566 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.24 Å)

Structure validation