4HYT
Na,K-ATPase in the E2P state with bound ouabain and Mg2+ in the cation-binding site
Summary for 4HYT
Entry DOI | 10.2210/pdb4hyt/pdb |
Related | 3KDP 3N23 |
Descriptor | Sodium/potassium-transporting ATPase subunit alpha-1, O-[(S)-({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine, O-DODECANYL OCTAETHYLENE GLYCOL, ... (13 entities in total) |
Functional Keywords | membrane transporter, hydrolase-membrane protein complex, hydrolase/membrane protein |
Biological source | Sus scrofa (pig) More |
Total number of polymer chains | 6 |
Total formula weight | 320755.17 |
Authors | Laursen, M.,Yatime, L.,Nissen, P.,Fedosova, N.U. (deposition date: 2012-11-14, release date: 2013-06-26, Last modification date: 2023-09-20) |
Primary citation | Laursen, M.,Yatime, L.,Nissen, P.,Fedosova, N.U. Crystal structure of the high-affinity Na+,K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site. Proc.Natl.Acad.Sci.USA, 110:10958-10963, 2013 Cited by PubMed: 23776223DOI: 10.1073/pnas.1222308110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.404 Å) |
Structure validation
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