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4HD9

Crystal structure of native human MAdCAM-1 D1D2 domain

Summary for 4HD9
Entry DOI10.2210/pdb4hd9/pdb
Related4HBQ 4HCR
DescriptorMucosal addressin cell adhesion molecule 1, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywordsimmunoglobulin superfamily, rolling and firm adhesion, integrin alpha4beta7, immune system
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein: Q13477
Total number of polymer chains1
Total formula weight22569.52
Authors
Springer, T.,Yu, Y.,Zhu, J. (deposition date: 2012-10-02, release date: 2013-01-23, Last modification date: 2024-10-30)
Primary citationSpringer, T.,Yu, Y.,Zhu, J.,Wang, J.-H.,Huang, P.-S.
A Different Fold with an Integrin-Binding Loop Specialized for Flexibility in Mucosal Addressin Cell Adhesion Molecule-1
TO BE PUBLISHED,
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

226707

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