4GXB

Structure of the SNX17 atypical FERM domain bound to the NPxY motif of P-selectin

Summary for 4GXB

Entry DOI	10.2210/pdb4gxb/pdb
Related	1HES 3FOG 3LUI
Descriptor	Sorting nexin-17, P-selectin, GLYCEROL, ... (4 entities in total)
Functional Keywords	ferm domain, protein transport-cell adhesion complex, protein transport/cell adhesion
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: Q15036 Membrane; Single-pass type I membrane protein: Q01102
Total number of polymer chains	2
Total formula weight	36366.47
Authors	Ghai, R.,Bugarcic, A.,Liu, H.,Norwood, S.J.,Li, S.S.,Teasdale, R.D.,Collins, B.M. (deposition date: 2012-09-04, release date: 2013-03-13, Last modification date: 2024-03-20)
Primary citation	Ghai, R.,Bugarcic, A.,Liu, H.,Norwood, S.J.,Skeldal, S.,Coulson, E.J.,Li, S.S.,Teasdale, R.D.,Collins, B.M. Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Proc.Natl.Acad.Sci.USA, 110:E643-E652, 2013 Cited by PubMed: 23382219 DOI: 10.1073/pnas.1216229110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation