4GWD

Crystal Structure of the Mn2+2,Zn2+-Human Arginase I-ABH Complex

Summary for 4GWD

Entry DOI	10.2210/pdb4gwd/pdb
Related	2AEB 4GSZ 4GWC
Descriptor	Arginase-1, MANGANESE (II) ION, ZINC ION, ... (5 entities in total)
Functional Keywords	arginase fold, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P05089
Total number of polymer chains	2
Total formula weight	70294.32
Authors	D'Antonio, E.L.,Hai, Y.,Christianson, D.W. (deposition date: 2012-09-01, release date: 2012-09-26, Last modification date: 2023-09-13)
Primary citation	D'Antonio, E.L.,Hai, Y.,Christianson, D.W. Structure and function of non-native metal clusters in human arginase I. Biochemistry, 51:8399-8409, 2012 Cited by PubMed: 23061982 DOI: 10.1021/bi301145n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.53 Å)

Structure validation