4GBX

Crystal structure of an immune complex at pH 6.5

Summary for 4GBX

• Entry DOI: 10.2210/pdb4gbx/pdb
• Descriptor: HLA class II histocompatibility antigen, DM alpha chain, HLA class II histocompatibility antigen, DM beta chain, HLA class II histocompatibility antigen, DR alpha chain, ... (7 entities in total)
• Functional Keywords: immune complex, peptide loading, peptide editing, antigen presentation, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 92814.37

Authors

Sethi, D.K.,Pos, W.,Wucherpfennig, K.W. (deposition date: 2012-07-28, release date: 2013-01-16, Last modification date: 2020-07-29)

• Primary citation: Pos, W.,Sethi, D.K.,Call, M.J.,Schulze, M.S.,Anders, A.K.,Pyrdol, J.,Wucherpfennig, K.W.; Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.; Cell(Cambridge,Mass.), 151:1557-1568, 2012; PubMed: 23260142; DOI: 10.1016/j.cell.2012.11.025

Experimental method

X-RAY DIFFRACTION (3 Å)