4F93

Brr2 Helicase Region S1087L, Mg-ATP

Summary for 4F93

• Entry DOI: 10.2210/pdb4f93/pdb
• Related: 4F91 4F92
• Descriptor: U5 small nuclear ribonucleoprotein 200 kDa helicase, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: rnp remodeling, pre-mrna splicing, spliceosome catalytic activation, dexd/h-box rna helicase, rna and atp binding, nucleus, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O75643
• Total number of polymer chains: 1
• Total formula weight: 198395.20

Authors

Santos, K.F.,Jovin, S.M.,Weber, G.,Pena, V.,Luehrmann, R.,Wahl, M.C. (deposition date: 2012-05-18, release date: 2012-10-17, Last modification date: 2024-02-28)

• Primary citation: Santos, K.F.,Jovin, S.M.,Weber, G.,Pena, V.,Luhrmann, R.,Wahl, M.C.; Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.; Proc.Natl.Acad.Sci.USA, 109:17418-17423, 2012; PubMed: 23045696; DOI: 10.1073/pnas.1208098109

Experimental method

X-RAY DIFFRACTION (2.92 Å)