4EQ1
Crystal Structure of the ARNT PAS-B homodimer
Summary for 4EQ1
Entry DOI | 10.2210/pdb4eq1/pdb |
Related | 1X0O 2B02 2HV1 2K7S 3F1N 3F1O 3F1P 3H7W 3H82 |
Descriptor | Aryl hydrocarbon receptor nuclear translocator, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL (3 entities in total) |
Functional Keywords | per-arnt-sim, transcription regulation, homodimer, transcription factor, dna-binding, hif1, hif2, ahr, transcription |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P27540 |
Total number of polymer chains | 2 |
Total formula weight | 26099.60 |
Authors | Gardner, K.H.,Key, J.M. (deposition date: 2012-04-17, release date: 2013-04-17, Last modification date: 2023-09-13) |
Primary citation | Guo, Y.,Partch, C.L.,Key, J.,Card, P.B.,Pashkov, V.,Patel, A.,Bruick, R.K.,Wurdak, H.,Gardner, K.H. Regulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules. Acs Chem.Biol., 8:626-635, 2013 Cited by PubMed: 23240775DOI: 10.1021/cb300604u PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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