4EJI

Human Cytochrome P450 2A13 in complex with two molecules of 4-(methylnitrosamino)-1-(3-puridyl)-1-butanone

Summary for 4EJI

Entry DOI	10.2210/pdb4eji/pdb
Related	2P85 3T3S 4EJG 4EJH 4EJJ
Descriptor	Cytochrome P450 2A13, PROTOPORPHYRIN IX CONTAINING FE, 4-[methyl(nitroso)amino]-1-(pyridin-3-yl)butan-1-one, ... (4 entities in total)
Functional Keywords	cyp2a13, cytochrome p450 2a13, p450 2a13, heme protein, monooxygenase, drug metabolism, xenobiotic metabolism, endoplasmic reticulum, membrane, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Endoplasmic reticulum membrane; Peripheral membrane protein: Q16696
Total number of polymer chains	1
Total formula weight	55835.70
Authors	DeVore, N.M.,Scott, E.E. (deposition date: 2012-04-06, release date: 2012-06-06, Last modification date: 2023-09-13)
Primary citation	DeVore, N.M.,Scott, E.E. Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone binding and access channel in human cytochrome P450 2A6 and 2A13 enzymes. J.Biol.Chem., 287:26576-26585, 2012 Cited by PubMed: 22700965 DOI: 10.1074/jbc.M112.372813 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation