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4DOA

Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate: non-interactive binding of s-isomer

Summary for 4DOA
Entry DOI10.2210/pdb4doa/pdb
Related4DO9 4DOB 4DOC
DescriptorDNA polymerase beta, C C G A C C G C G C A T C A G C, G C T G A T G C G (DOC), ... (9 entities in total)
Functional Keywordsstereoselectivity, polymerase, dna polymerase, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus: P06746
Total number of polymer chains4
Total formula weight48445.58
Authors
Batra, V.K. (deposition date: 2012-02-09, release date: 2012-06-13, Last modification date: 2023-09-13)
Primary citationWu, Y.,Zakharova, V.M.,Kashemirov, B.A.,Goodman, M.F.,Batra, V.K.,Wilson, S.H.,McKenna, C.E.
Beta,gamma-CHF- and beta,gamma-CHCl-dGTP Diastereomers: Synthesis, Discrete (31)P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA Polymerases
J.Am.Chem.Soc., 134:8734-8737, 2012
Cited by
PubMed: 22397499
DOI: 10.1021/ja300218x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.051 Å)
Structure validation

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